Aconite – a Poison, or a Medicine? Ancient and Early Byzantine Testimonies
DOI:
https://doi.org/10.18778/2084-140X.12.24Keywords:
aconite, ancient medicine, Byzantine medicine, toxicology, Roman law, Byzantine lawAbstract
Aconite (Aconitum napellus) was one of the most notorious, poisonous plants in the ancient world. Its dangerous, lethal power – present in leaves, roots, stem, and tuber – was well known to the Greeks and the Romans from the earliest times. Evidence of this phenomenon is not only present in archaeological findings, but also in many writings – biographies, poems, legal codes, etc.
However, the most precise and detailed accounts come from treatises written by botanists, physicians and encyclopaedists, like Theophrastus, Nicander, Pliny the Elder, Dioscorides, or Galen, and by early Byzantine authors, Oribasius, Aetius of Amida, and Paul of Aegina. In their testimonies, one can find descriptions of aconite, its influence on the human body (and animals), and remedies for affected people.
In contrast, there are few passages from these sources that inform the readers about the healing properties of aconite. According to these fragments, carefully administered, aconite could be helpful in some therapies, but its use was extremely hazardous, as even a small part of the plant could kill a man.
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References
Aetii Amideni libri medicinales I–VIII, ed. A. Olivieri, Lipsiae–Berolini 1935–1950 [= Corpus Medicorum Graecorum, 8].
Andocides, Orationes, ed. F. Blass, C. Fuhr, Stutgardiae 1966.
Appendix Eclogae, [in:] Fontes Minores III, ed. L. Burgmann, S. Troianos, Frankfurt am Main 1974.
Athenaeus, The Learned Banqueters, vol. I–VIII, ed. S. Douglas Olson, Cambridge Mass. 2006–2012 [= Loeb Classical Library], https://doi.org/10.4159/DLCL.atheneus_grammarian-learned_banqueters.2007 DOI: https://doi.org/10.4159/DLCL.atheneus_grammarian-learned_banqueters.2007
Ausonius, Technopaegnion, [in:] Ausonius, vol. I, trans. H. G.E. White, Cambridge Mass. 1919 [= Loeb Classical Library, 96], https://doi.org/10.4159/DLCL.ausonius-technopaegnion.1919 DOI: https://doi.org/10.4159/DLCL.ausonius-technopaegnion.1919
Basilica, vol. I–VIII, ed. H. J. Scheltema, N. van der Wal, Groningen 1955–1988.
The Digest of Justinian, vol. IV, ed. T. Mommsen, P. Krueger, trans. A. Watson, Philadelphia 1985.
Digesta Iustiniani Augusti, rec. T. Mommsen, Berolini 1870.
Diogenes Laertius, Vitae philosophorum, vol. I, ed. M. Marcovich, Stuttgart–Leipzig 1999 [= Bibliotheca scriptorum Graecorum et Romanorum Teubneriana].
Dioscorides, De materia medica: being an Herbal with Many Other Medicinal Materials. Written in Greek in the First Century of the Common Era, ed., trans. T. A. Osbaldeston, R. P.A. Wood, Johannesburg 2000.
Dioscórides, Plantas y remedios medicinales, vol. IV–V, trans. M. G. Valdés, Madrid 1998.
Galeni De antidotis libri II, [in:] Claudii Galeni opera omnia, vol. XIV, ed. C. G. Kühn, Lipsiae 1827.
Galeni De compositione medicamentorum secundum locos, [in:] Claudii Galeni opera omnia, vol. XII–XIII, ed. C. G. Kühn, Lipsiae 1826–1827.
Galeni De simplicium medicamentorum temperamentis ac facultatibus libri XI, [in:] Claudii Galeni opera omnia, vol. XI–XII, ed. C. G. Kühn, Lipsiae 1826–1827.
Galeni In Hippocratis sextum librum epidemiarum commentaria I–VI, ed. E. Wenkebach, Leipzig 1940.
Juvenal, Satirae, [in:] Juvenal and Persius, ed. S. Morton Braund, Cambridge Mass. 2004 [= Loeb Classical Library, 91], https://doi.org/10.4159/DLCL.juvenal-satires.2004 DOI: https://doi.org/10.4159/DLCL.juvenal-satires.2004
Macrobius, Saturnalia, vol. I–III, ed. R. A. Kaster, Cambridge Mass. 2011 [= Loeb Classical Library, 510–512], https://doi.org/10.4159/DLCL.macrobius-saturnalia.2011 DOI: https://doi.org/10.4159/DLCL.macrobius-saturnalia.2011
Nicandre, Les alexipharmaques, [in:] Nicandre, Oeuvres, vol. II, trans. J.-M. Jacques, Paris 2002.
Nicandre, Les alexipharmaques, [in:] Nicandre, Oeuvres, vol. III, trans. J.-M. Jacques, Paris 2007.
Nomocanon, [in:] Collectio Tripartita: Justinian on Religious and Ecclesiastical Affairs, ed. B. H. Stolte, N. van der Wal, Groningen 1994.
Oribasii collectionum medicarum reliquiae, vol. I–IV, ed. I. Raeder, Lipsiae–Berolini 1928–1933 [= Corpus Medicorum Graecorum].
Oribasii eclogae medicamentorum, [in:] Oribasii Collectionum medicarum reliquiae, vol. IV, Libri XLIX–L, libri incerti, eclogae medicamentorum, ed. J. Raeder, Leipzig–Berlin 1933 [= Corpus Medicorum Graecorum].
Ovid, Metamorphoses. Books 1–8, trans. F. J. Miller, rev. G. P. Goold, Cambridge Mass. 1977 [= Loeb Classical Library].
Paulus Aegineta, vol. I–II, ed. I. L. Heiberg, Lipsiae–Berolini 1921–1924.
Pedanii Dioscuridis Anazarbei de materia medica libri V, vol. I–III, ed. M. Wellmann, Berolini 1906–1914.
Pedanius Dioscorides of Anazarbus, De materia medica, trans. L. Y. Beck, Hildesheim 2020.
Pliny the Elder, Natural History, vol. I–IX, trans. H. Rackham, W. H.S. Jones, D. E. Eichholz, Cambridge Mass. 1938–1963 [= Loeb Classical Library], https://doi.org/10.4159/DLCL.pliny_elder-natural_history.1938 DOI: https://doi.org/10.4159/DLCL.pliny_elder-natural_history.1938
Plutarch, Crassus, [in:] Plutarch, Lives, vol. III, trans. B. Perrin, Cambridge Mass. 1916 [= Loeb Classical Library, 65].
Plutarch, Demetrius, [in:] Plutarch, Lives, vol. IX, trans. B. Perrin, Cambridge Mass. 1920 [= Loeb Classical Library, 101].
Prochiron Auctum, ed. P. Zepos, Athens 1931.
Prochiron Legum vel Prochiron Calabriae, ed. F. Brandileone, V. Puntoni, Roma 1895.
Scribonio Largo, Ricette mediche, trans. S. Sconocchia, Berlin 2020 [= Corpus medicorum Latinorum].
Servii Grammatici in Vergili Bucolica et Georgica commentarii, rec. G. Thilo, Lipsiae 1887.
Strabonis geographica, vol. I–III, ed. A. Meineke, Graz 1969.
Synopsis basilicorum sive synopsis major, ed. P. Zepos, Athens 1931.
Théophraste, Recherches sur les plantes, vol. V, Livre IX, trans. S. Amigues, Paris 2006.
Theophrastus, Enquiry into Plants, [in:] Theophrastus, Enquiry into Plants and Minor Works, ed. A. Hort, Cambridge Mass. 1926.
Amigues S., Commentaire, [in:] Théophraste, Recherches sur les plantes, vol. V, Livre IX, trans. S. Amigues, Paris 2006, p. 65–242.
Been A., Aconitum: Genus of Powerful and Sensational Plants, “Pharmacy in History” 34.1, 1992, p. 35–39.
Chan T. Y.K., Aconite Poisoning, “Clinical Toxicology” 47, 2009, p. 279–285, https://doi.org/10.1080/15563650902904407 DOI: https://doi.org/10.1080/15563650902904407
Cilliers L., Retief F., Poisons, Poisoners, and Poisoning in Ancient Rome, [in:] History of Toxicology and Environmental Health. Toxicology in Antiquity, vol. I, ed. P. Wexler, Amsterdam 2014, p. 127–137, https://doi.org/10.1016/B978-0-12-800045-8.00013-7 DOI: https://doi.org/10.1016/B978-0-12-800045-8.00013-7
Deichmann W. B., Henschler D., Holmstedt B., Keil G., What is there that is not Poison? A Study of the Third Defense by Paracelsus, “Archives of Toxicology” 58, 1986, p. 207–213, https://doi.org/10.1007/BF00297107 DOI: https://doi.org/10.1007/BF00297107
Diccionario griego-español, vol. I, ed. F. R. Adrados, Madrid 1989.
Dybała J., Kokoszko M., Lecznicze działanie olei roślinnych na podstawie De materia medica Dioskuridesa, [in:] Lek roślinny, vol. VI, red. B. Płonka-Syroka, A. Syroka, Wrocław 2017, p. 81–93.
Fausti D., La botanica medica di età imperiale. Piante narcotiche dal quarto libro di Dioscoride, [in:] Περὶ φυτῶν Trattati greci di botanica in Occidente e in Oriente, ed. M. F. Ferrini, G. Giglioni, Macerata 2020, p. 43–73.
Jacques J.-M., Notice, [in:] Nicandre, Oeuvres, vol. II, trans. J.-M. Jacques, Paris 2002.
Jauregui M. G., The Biological Assay of Aconite, “Journal of the American Pharmaceutical Association” 16.11, 1927, p. 1045–1052, https://doi.org/10.1002/jps.3080161106 DOI: https://doi.org/10.1002/jps.3080161106
Jones-Lewis M., Pharmacy, [in:] A Companion to Science, Technology, and Medicine in Ancient Greece and Rome, vol. I, ed. G. L. Irby, Malden–Oxford 2016 [= Blackwell Companions to the Ancient World], p. 402–417, https://doi.org/10.1002/9781118373057.ch25 DOI: https://doi.org/10.1002/9781118373057.ch25
Kaufman D. B., Poisons and Poisoning among the Romans, “Classical Philology” 27.2, 1932, p. 156–167, https://doi.org/10.1086/361458 DOI: https://doi.org/10.1086/361458
Kokoszko M., Jagusiak K., Galen on Wine, or Some Traces of Preference, “Piotrkowskie Zeszyty Historyczne” 2020, special issue, p. 9–28.
Laskaris J., Metals in Medicine: from Telephus to Galen, [in:] Popular Medicine in Graeco-Roman Antiquity: Explorations, ed. W. V. Harris, Leiden–Boston 2016 [= Columbia Studies in the Classical Tradition, 42], p. 147–160, https://doi.org/10.1163/9789004326040_007 DOI: https://doi.org/10.1163/9789004326040_007
Lewkowicz-Mosiej T., Rośliny lecznicze, Warszawa 2012.
Liddell H. G., Scott R., Jones H. S. et al., A Greek-English Lexicon, 9Oxford 1996.
Mayor A., Mithridates of Pontus and his Universal Antidote, [in:] History of Toxicology and Environmental Health. Toxicology in Antiquity, vol. I, ed. P. Wexler, Amsterdam 2014, p. 21–34, https://doi.org/10.1016/B978-0-12-800045-8.00004-6 DOI: https://doi.org/10.1016/B978-0-12-800045-8.00004-6
Moritz F., Compagnon P., Guery Kaliszczak I., Kaliszczak Y., Caliskan V., Girault C., Severe Acute Poisoning with Homemade Aconitum napellus Capsules: Toxicokinetic and Clinical Data, “Clinical Toxicology” 43, 2005, p. 873–876, https://doi.org/10.1080/15563650500357594 DOI: https://doi.org/10.1080/15563650500357594
Nadlewska A., Ładny J. R., Wojewódzka-Żelezniakowicz M., Czaban S. L., Kosierkiewicz W., Szymańska A., Łukasik-Głębocka M., Naskręt M., Górny J., Trucizny – definicja, rodzaje, mechanizm działania, “Postępy Nauk Medycznych” 9, 2010, p. 704–708.
Nepovimova E., Kuca K., The History of Poisoning: from Ancient Times until Modern Era, “Archives of Toxicology” 93, 2019, p. 11–24, https://doi.org/10.1007/s00204-018-2290-0 DOI: https://doi.org/10.1007/s00204-018-2290-0
Puri H. S., Uses of Aconites, “Journal d’agriculture tropicale et de botanique appliquée” 21.7, 1974, p. 239–246, https://doi.org/10.3406/jatba.1974.3168 DOI: https://doi.org/10.3406/jatba.1974.3168
Riddle J. M., Dioscorides on Pharmacy and Medicine, Austin 1985, https://doi.org/10.7560/715448 DOI: https://doi.org/10.7560/715448
Scarborough J., Drugs and Medicines in the Roman World, “Expedition” 38.2, 1996, p. 38–51. DOI: https://doi.org/10.2165/00003495-199600511-00008
Scarborough J., Drugs for an Emperor, “Amphora. A Publication of the American Philological Association” 3.1, 2004, p. 4–5, 17.
Scarborough J., Herbs of the Field and Herbs of the Garden in Byzantine Medicinal Pharmacy, [in:] Byzantine Garden Culture, ed. A. Littlewood, H. Maguire, J. Wolschke-Bulmahn, Washington DC 2002, p. 177–188.
Scarborough J., Theophrastus on Herbals and Herbal Remedies, “Journal of the History of Biology” 11.2, 1978, p. 353–385, https://doi.org/10.1007/BF00389304 DOI: https://doi.org/10.1007/BF00389304
Shoaib A., Siddiqui H. H., Dixit R. K., Siddiqui S., Deen B., Khan A., Alrokayan S. H., Khan H. A., Ahmad P., Neuroprotective Effects of Dried Tubers of Aconitum napellus, “Plants” 9.3, 2020, art. 356, https://doi.org/10.3390/plants9030356 DOI: https://doi.org/10.3390/plants9030356
Singh M. K., Vinod M., Iyer S. K., Khare G., Sharwan G., Larokar Y. K., Aconite: a Pharmacological Update, “International Journal of Research in Pharmaceutical Sciences” 3.2, 2012, p. 242–246.
Skaltsa H., Philianos S., Papaphilippou G., L’aconit chez Nicandre et de nos jours, “Revue d’histoire de la pharmacie” 85.316, 1997, p. 405–410, https://doi.org/10.3406/pharm.1997.4893 DOI: https://doi.org/10.3406/pharm.1997.4893
Szweykowska A., Szweykowski J., Botanika. Systematyka, vol. II, Warszawa 2012.
Tai C.-J., El-Shazly M., Wu T.-Y., Lee K.-T., Csupor D., Hohmann J., Chang F.-R., Wu Y.-C., Clinical Aspects of Aconitum Preparations, “Planta Medica” 81, 2015, p. 1017–1028, https://doi.org/10.1055/s-0035-1546183 DOI: https://doi.org/10.1055/s-0035-1546183
Takacs M., Frass M., Walderf G., Fibert P., Rottensteiner M., Glück W., Lechleitner P., Oberbaum M., Leisseri I., Chandak K., Panhofer P., Weiermayer P., Adjunctive Homeopathic Treatment of Hospitalized COVID-19 Patients (COVIHOM): A Retrospective Case Series, “Complementary Therapies in Clinical Practice” 44, 2021, p. 1–11, https://doi.org/10.1016/j.ctcp.2021.101415 DOI: https://doi.org/10.1016/j.ctcp.2021.101415
Totelin L., Botanizing Rulers and their Herbal Subjects: Plants and Political Power in Greek and Roman Literature, “Phoenix” 66.1–2, 2012, p. 122–144, https://doi.org/10.1353/phx.2012.0013 DOI: https://doi.org/10.1353/phx.2012.0013
Touwaide A., Murder, Execution, and Suicide in Ancient Greece and Rome, [in:] History of Toxicology and Environmental Health. Toxicology in Antiquity, vol. II, ed. P. Wexler, Amsterdam 2015, p. 1–8, https://doi.org/10.1016/B978-0-12-801506-3.00001-7 DOI: https://doi.org/10.1016/B978-0-12-801506-3.00001-7
Tsoucalas G., Sgantzos M., The Death of Cleopatra: Suicide by Snakebite or Poisoned by her Enemies?, [in:] History of Toxicology and Environmental Health. Toxicology in Antiquity, vol. I, ed. P. Wexler, Amsterdam 2014, p. 11–20, https://doi.org/10.1016/B978-0-12-800045-8.00002-2 DOI: https://doi.org/10.1016/B978-0-12-800045-8.00002-2
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